Research Teams

Research Overview

The University of Louisville is a leader in advancing neuroscience through interdisciplinary research, clinical innovation and translational science. Through multiple NIH and Foundation-funded research teams, labs and clinical trials, the UofL Department of Neurological Surgery and Division of Physical Medicine and Rehabilitation are dedicated to advancing our fields. Key areas of research include:

Spinal Cord Injury and Recovery

• Conducted through the Kentucky Spinal Cord Injury Research Center (KSCIRC).
• Focus on neuroplasticity, locomotor training and neuromodulation to restore standing and walking in individuals with spinal cord injuries.
• Investigate secondary complications such as autonomic dysfunction, cardiovascular regulation and gastrointestinal motility.

Movement Disorders and Deep Brain Stimulation (DBS)

• Research on Parkinson’s disease, essential tremor and dystonia.
• Development and refinement of DBS protocols to improve motor function and quality of life.
• Collaborative work between the Division of Movement Disorders and the neurosurgery faculty.

Neurophysiology and Cognitive Function

• Studies on brain function, cognitive processing and neural circuitry.
• Use of advanced imaging and electrophysiological tools to understand how the brain adapts to injury and therapy.

Translational Neuroscience

• Bridging basic science and clinical application to develop novel therapies.
• Includes gene therapy, stem cell research and biomaterials for neural repair.

Sports Cognition

• UofL is home to a unique program in sports cognition. Our scientists are actively studying what cognitive abilities differentiate the most able athletes and how these techniques can be learned and improved.
• Faculty within the Department of Neurological Surgery are actively working with our top-ranked UofL sports teams and our Department of Sports Medicine. Together, they are advancing the science of elite performance.  

Neuro-oncology and Brain Tumor Research

• Focus on gliomas, meningiomas and metastatic brain tumors.
• Integration of GammaTile therapy and other advanced surgical techniques for targeted treatment.

Rehabilitation and Functional Recovery

• Collaborative work with Frazier Rehabilitation Institute to optimize recovery after neurological injury.
• Emphasis on multidisciplinary care, including physical therapy, occupational therapy and neuropsychology.