Pediatric Research Institute
Advancing child health through groundbreaking research, innovation and collaboration to improve outcomes for children and families everywhere.
Department of Pediatrics Basic Science and Clinical and Translations Research Units
Advancing child health through high-impact research in sleep, diabetes, tumor biology and outcomes. We bridge lab and clinic with strong infrastructure, collaboration and mentorship to shape the future of pediatric science.
Featured research and projects
The Pediatric Research Institute, led by vice president of research, Kyle Brothers, unites groundbreaking discovery and real-world impact. Home to the Basic Science Research Unit, directed by Lu Cai, and the Clinical and Translational Research Unit, also led by Brothers, the Institute drives innovation from the lab bench to the bedside to transform child health.
Fibroblast growth factor 1 prevents hyperlipidemia and atherosclerosis
This project is to define how FGF1 protects against atherosclerosis.
A novel mechanism of stromal cell derived factor 1 protection against diabetic cardiomyopathy
The goal of this project is to define whether SDF-1 protects diabetic heart via activation of CXCR7.
FGF1 Prevents Doxorubicin-Induced Cardiotoxicity in Pediatric Cancer Survivors
The goal of this project is to test the efficacy for FGF1 preventing DICM in young-tumor-bearing mice that mimic pediatric cancer survivors.
Statistics
6
Faculty
49
Publications since 2022
$17M
in Research Funding
Recent News
At the heart of care: Thanking our residents and fellows
02/27/26
School of Medicine
UofL cancer researchers among top 1% most-cited in the world
02/24/26
Research & Innovation
Sharing the pulse of surgery
02/24/26
Department of Cardiovascular and Thoracic Surgery
Events
Mar
05
Flourishing Together
01:30 PM - 03:30 PM
Mar
05
Flourishing Together
06:30 PM - 08:30 PM
Mar
12
Flourishing Together
01:30 PM - 03:30 PM